Categoría: "Inmunología"

376 contenidos encontrados.
Centro Investigación en Educación Superior

Computer-aided design of T-cell epitope-based vaccines: addressing population coverage

Epitope-based vaccines (EVs) make use of short antigen-derived peptides corresponding to immune epitopes, which are administered to trigger a protective humoral and/or […]

Centro Investigación en Educación Superior

A bioinformatics tool for epitope-based vaccine design that accounts for human ethnic diversity: Application to emerging infectious diseases

Background: Peptide vaccination based on multiple T-cell epitopes can be used to target well-defined ethnic populations. Because the response to […]

Centro Investigación en Educación Superior

Frequency and Specificity of Red Blood Cell Alloimmunization in Chilean Transfused Patients

Alloimmunization is an adverse effect of blood transfusions. In Chile, alloimmunization frequency is not established, and for this reason the […]

Centro Investigación en Educación Superior

Opposing roles of interferon-gamma on cells of the central nervous system in autoimmune neuroinflammation

Multiple sclerosis (MS) is the principal cause of autoimmune neuroinflammation in humans, and its animal model, experimental autoimmune encephalomyelitis (EAE), […]

Centro Investigación en Educación Superior

Stage-specific role of interferon-gamma in experimental autoimmune encephalomyelitis and multiple sclerosis

The role of interferon (IFN)-γ in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), has remained as […]

Centro Investigación en Educación Superior

COST-UTILITY ANALYSIS OF PNEUMOCOCCAL VACCINATION WITH PCV13 VERSUS PPSV23 IN ADULTS OVER 18 YEARS OLD IN CHILE

Pneumococcal infections are a public health concern, especially among older adults and those with underlying comorbid or immunocompromising conditions. In […]

Centro Investigación en Educación Superior

Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse

B-cell receptor (BCR) engagement with surface-tethered antigens leads to the formation of an immune synapse, which facilitates antigen uptake for […]

Centro Investigación en Educación Superior

Dopamine receptors D3 and D5 regulate CD4 +T-cell activation and differentiation by modulating ERK activation and cAMP productionDopamine receptors D3 and D5 regulate CD4 +T-cell activation and differentiation by modulating ERK activation and cAMP production

Dopamine receptors have been described in T-cells, however their signalling pathwayscoupled remain unknown. Since cAMP and ERKs play key roles regulating T-cellphysiology, we aim to determine whether cAMP […]

376 contenidos encontrados.
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