Novel vaccination approaches based on rational design of B- and T-cell epitopes – epitope-based vaccines – are making progress in […]
Astrocytes exert multiple functions in the brain such as the development of blood–brain barrier characteristics, the promotion of neurovascular coupling, […]
Maternal physiological hypercholesterolemia occurs during pregnancy, ensuring normal fetal development. In some cases, the maternal plasma cholesterol level increases to above this physiological range, leading to maternal supraphysiological hypercholesterolemia (MSPH). This […]
The human insulin receptor (IR) exists in two isoforms that differ by the absence (IR-A) or the presence (IR-B) of […]
La vasculogénesis es controlada por una serie de mecanismos que se activan en función del tiempo y del espacio durante […]
Alloimmunization is an adverse effect of blood transfusions. In Chile, alloimmunization frequency is not established, and for this reason the […]
Fibroblasts are critical for wound contraction; a pivotal step in wound healing. They produce and modify the extracellular matrix (ECM) […]
Angiogenesis is a key process by which new capillary blood vessels are formed, sustaining the supply of oxygen and other […]
La funcionalidad de la célula eucariota depende de la membrana celular, de la información genética y de la acción de […]
BACKGROUND The impairment of 11β-hydroxysteroid dehydrogenase type 2 enzyme (11βHSD2) results in an inefficient conversion of cortisol to cortisone, which […]
